research staff

of Chair and Department of Pharmacognosy, Wroclaw Medical University
Gleńsk Michał PhD
assistant professor / lecturer
tel. +48 71 78 40 223, e-mail
research
  • triterpenes (mostly saponins) and their biological properties (antiinflamatory and cytotoxic activity)
  • TLC with solid phase gradient, 2D TLC (Two-dimensional planar chromatography)
practice
  • countercurrent chromatography - Planta Analytica, USA
  • countercurrent chromatography - Armen-Instrument, France
  • isolation and determination of triterpenes structures - Pharmaceutical Biology, Ernst-Moritz-Arndt-Universität Greifswald, Germany
  • isolation and investigation of saponins - Institute of Soil Science and Plant Cultivation, Puławy, Poland
didactics
  • pharmacognosy and phytotherapy classes
  • promotion of master's theses
  • optional courses
other information
  • 1999 - PhD (pharmacy)
  • 1992 - employment in Medical University
  • 1999 - MSc (pharmacy)
publications
experimental
  • Gleńsk Michał, Gajda Beata, Franiczek Roman, Krzyżanowska Barbara, Biskup Izabela, Włodarczyk Maciej
    In vitro evaluation of the antioxidant and antimicrobial activity of DIMBOA [2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one]
    Natural Product Research 2016; 30(11): 1305-1308
  • Gleńsk Michał, Gliński Jan A., Jamróz Marta, Stefanowicz Piotr, Kaźmierski Sławomir
    Phenolic constituents from Alchornea castaneifolia
    Records of Natural Products 2016; 10(1): 32-39
  • Franiczek Roman, Gleńsk Michał, Krzyżanowska Barbara, Włodarczyk Maciej
    β-Aescin at subinhibitory concentration (sub-MIC) enhances susceptibility of Candida glabrata clinical isolates to nystatin
    Medical Mycology 2015; 53(8): 845-851
  • Zagaja Mirosław, Andres-Mach Marta, Skalicka-Woźniak Krystyna, Rękas Anna, Kondrat-Wróbel Maria, Gleńsk Michał, Łuszczki Jarogniew
    Assessment of the Combined Treatment with Umbelliferone and Four Classical Antiepileptic Drugs Against Maximal Electroshock-Induced Seizures in Mice
    Pharmacology 2015; 96(3-4): 175-180
  • Zagaja Mirosław, Pyrka Daniel, Skalicka-Woźniak Krystyna, Głowniak Kazimierz, Florek-Łuszczki Magdalena, Gleńsk Michał, Łuszczki Jarogniew
    Effect of xanthotoxin (8-methoxypsoralen) on the anticonvulsant activity of classical antiepileptic drugs against maximal electroshock-induced seizures in mice
    Fitoterapia 2015; 105: 1-6
  • Gleńsk Michał, Gliński Jan, Włodarczyk Maciej Stefanowicz Piotr
    Determination of ursolic and oleanolic acid in Sambuci fructus
    Chemistry & Biodiversity 2014; 11(12): 1939-1944
  • Seweryn Ewa, Gleńsk Michał, Środa-Pomianek Kamila, Ceremuga Ireneusz, Włodarczyk Maciej, Gamian Andrzej
    Cytotoxic effects of four aescin types on human colon adenocarcinoma cell lines
    Natural Product Communications 2014; 9(3): 387-390
  • Łuszczki Jarogniew, Włodarczyk Maciej, Gleńsk Michał, Marzęda Ewa, Durmowicz Dariusz, Florek-Łuszczki Magdalena
    Effects of alizarin, betulin, curcumin, diosmin , linalool, menthofuran, α-terpineol, theobromine, β-thujaplicin and vanillin against maximal electroshock-induced seizures in mice
    Journal of Pre-Clinical and Clinical Research, 2013; 7(1): 40-42
  • Łuszczki Jarogniew, Włodarczyk Maciej, Gleńsk Michał, Marzęda Ewa, Durmowicz Dariusz, Florek-Łuszczki Magdalena
    Effects of various naturally occurring compounds (arbutin, borneol, esculetin, esculin, ellagic acid, gallic acid, hesperidine, piperitol, piperonal, quercetin, thymoquinone and ursolic acid) against maximal electroshock-induced seizures in mice
    Current Issues in Pharmacy and Medical Sciences, 2013; 26(2): 135-139
  • Gleńsk Michał, Włodarczyk Maciej, Stefanowicz Piotr, Kucharska Alicja
    Biflavonoids from the Wollemi Pine, Wollemia nobilis (Araucariaceae)
    Biochemical Systematics and Ecology 2013; 46: 18-21
  • Berhow Mark, Polat Umit, Gliński Jan, Gleńsk Michal, Vaughn Steven, Isbell Terry, Ayala-Diaz Ivan, Marek Laura, Gardner Candice
    Optimized analysis and quantification of glucosinolates from Camelina sativa seeds by reverse-phase liquid chromatography
    Industrial Crops and Products 2013; 43: 119-125
  • Jamróz Marta, Jamróz Michał, Dobrowolski Jan, Gliński Jan, Gleńsk Michał
    One new and six known triterpene xylosides from Cimicifuga racemosa: FT-IR, Raman and NMR studies and DFT calculations
    Spectrochimica Acta A 2012; 93(1): 10-18
  • Gleńsk Michał, Włodarczyk Maciej, Basarello Carla, Pizza Cossimo
    Aescin determination in seeds and capsules of three pure and hybrid Aesculus species
    Chemistry of Natural Compounds 2011; 47(1): 142-143
  • Łuszczki Jarogniew, Marczewski Tadeusz , Mazurkiewicz Lech, Karwan Sławomir, Teresińska Maja, Florek-Łuszczki Magdalena, Gleńsk Michał
    Influence of osthole on the anticonvulsant activity of phenytoin and valproate in the maximal electroshock-induced seizures in mice
    Annales UMCS - Sectio DDD: Pharmacia 2011; 24(1): 33-44
  • Łuszczki Jarogniew, Andres-Mach Marta, Gleńsk Michał, Skalicka-Woźniak Krystyna
    Anticonvulsant effects of four linear furanocoumarins, bergapten, imperatorin, oxypeucedanin, and xanthotoxin, in the mouse maximal electroshock-induced seizure model: a comparative study
    Pharmacological Reports 2010; 62(6): 1231-1236
  • Łuszczki Jarogniew, Rękas Anna, Mazurkiewicz Lech, Gleńsk Michał, Ossowska Grażyna
    Effect of osthole on the protective activity of carbamazepine and phenobarbital against maximal electroshock-induced seizures in mice
    Annales UMCS - Sectio DDD: Pharmacia 2010; 23(3): 145-156
  • Gleńsk Michał, Włodarczyk Maciej, Bassarello Carla, Pizza Cosimo, Stefanowicz Piotr, Świtalska Marta
    A major saponin from leaves extract of Acer velutinum
    Zeitschrift für Naturforschung 2009; 64b(9): 1081-1086
  • Łuszczki Jarogniew, Wojda Ewa, Andres-Mach Marta, Cisowski Wojciech, Gleńsk Michał, Głowniak Kazimierz, Czuczwar Stanisław
    Anticonvulsant and acute neurotoxic effects of imperatorin, osthole and valproate in the maximal electroshock seizure and chimney tests in mice: a comparative study
    Epilepsy Research 2009; 85(2-3): 293-299
  • Zimecki Michał, Artym Jolanta, Cisowski Wojciech, Mażol Irena, Włodarczyk Maciej, Gleńsk Michał
    Immunomodulatory and anti-inflammatory activity of selected osthole derivatives
    Zeitschrift für Naturforschung 2009; 64c(5-6): 361-368
  • Frąckowiak Teresa, Bączek Tomasz, Kaliszan Roman, Żbikowska Beata, Gleńsk Michał, Fecka Izabela, Cisowski Wojciech
    Binding of an oxindole alkaloid from Uncaria tomentosa to amyloid protein (Aβ1-40)
    Zeitschrift für Naturforschung 2006; 61c(11-12): 821-826
  • Włodarczyk Maciej, Matysik Grażyna, Cisowski Wojciech, Gleńsk Michał
    Rapid densitometric quantitative screening of the myricitrin content of crude methanolic extracts of leaves from a variety of Acer species
    Journal of Planar Chromatography 2006; 19(5): 378-382
  • Cisowski Wojciech, Mażol Irena, Gleńsk Michał
    Investigation of the essential oils from three Cephalotaxus species
    Acta Poloniae Pharmaceutica 2005; 62(6): 461-463
  • Gleńsk Michał, Włodarczyk Maciej, Radom Monika, Cisowski Wojciech
    TLC as a rapid and convenient method for saponin investigation
    Journal of Planar Chromatography 2005; 18(2): 167-170
  • Wardencki Waldemar, Michulec Magdalena, Cisowski Wojciech, Gleńsk Michał, Żbikowska Beata
    Solvent residue determination in Uncaria tomentosa bark by HS-GC technique
    Chemia Analityczna 2005; 50(3): 575-581
  • Gleńsk Michał, Żbikowska Beata, Cisowski Wojciech
    TLC separation of Uncaria tomentosa alkaloids on chemically modified stationary phases
    Journal of Planar Chromatography 2004; 17(1): 14-17
  • Mażol Irena, Gleńsk Michał, Cisowski Wojciech
    Polyphenolic compounds from platycodon grandiflorum A. DC.
    Acta Poloniae Pharmaceutica 2004; 61(3): 203-208
  • Gleńsk Michał, Sawicka Urszula, Mażol Irena, Cisowski Wojciech
    2D TLC - graft planar chromatography in the analysis of a mixture of phenolic acids
    Journal of Planar Chromatography 2002, 15(6): 463-465
  • Gleńsk Michał, Biały Zbigniew, Jurzysta Marian, Cisowski Wojciech
    Two-dimensional TLC with a sorbent gradient for the analysis of alfalfa root saponins
    Chromatographia 2001; 54(9-10): 669-672
  • Gleńsk Michał, Czekalska Marlena, Cisowski Wojciech
    Resolution of saponins from a ginseng preparation by 2D TLC with an adsorbent gradient
    Journal of Planar Chromatography 2001; 14(6): 454-456
  • Gleńsk Michał, Wray Victor, Nimtz Manfred, Schöpke Thomas
    Triterpenoid saponins of Bellis perennis
    Scientia Pharmaceutica 2001; 69(1): 69-73
  • Gleńsk Michał, Cisowski Wojciech
    Two-dimensional TLC with an adsorbent gradient for analysis of saponins in Silene vulgaris Garcke
    Journal of Planar Chromatography 2000; 13(1): 9-11
  • Gąsiorowski Kazimierz, Brokos Barbara, Gleńsk Michał, Schöpke Thomas
    Immunomodulatory activity of the saponin-rich fraction from roots of Silene vulgaris Garcke: initial study
    Pharmazie 1999; 54(11): 864-866
  • Gleńsk Michał, Wray Victor, Nimtz Manfred, Schöpke Thomas
    Silenosides A-C, triterpenoid saponins from Silene vulgaris
    Journal of Natural Products 1999; 62(5): 717-721

monographs, elaborations, reviews
  • Cisowski Wojciech, Fecka Izabela, Gleńsk Michał
    Znaczenie bioflawonoidów w zapobieganiu niektórym schorzeniom cywilizacyjnym
    Roczniki Naukowe Wrocławskiego Oddziału Polskiego Towarzystwa Farmaceutycznego 2005; 10: 9-15

translations, edition
  • van Wyk Ben-Erik, Wink Michael
    Rośliny lecznicze świata. Ilustrowany przewodnik naukowy po najważniejszych roślinach leczniczych świata i ich wykorzystaniu
    (tłumaczenie z języka angielskiego i redakcja naukowa; praca zbiorowa:
    Fecka Izabela, Kowalczyk Adam, Gleńsk Michał, Raj Danuta, Turek Sebastian, Włodarczyk Maciej)
    MedPharm Polska, Wrocław 2008

textbooks
  • Gleńsk Michał, Raj Danuta, Włodarczyk Maciej
    Sproszkowane roślinne surowce lecznicze – klucz do rozpoznawania
    skrypt do nauki farmakognozji dla studentów farmacji
    Katedra i Zakład Farmakognozji AM we Wrocławiu, Wrocław, 2005
    (plik .pdf do pobrania - wersja '06, ~350 kB)

patents
  • Włodarczyk Maciej, Gleńsk Michał
    Sposób otrzymywania osajiny i pomiferyny
    BUP 2014.04.14, PL 401066 (A1)
    Application 2012.10.05
© MW 2005-2016     last update: 28.IX.2016     good ideas and comments here
www.fgz.lanet.wroc.net -> www.fgz.edu.pl